Amoxicillin and Clavulanate Potassium: Views of Amoxicillin and Clavulanate Potassium

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Amoxicillin and clavulanate potassium is also contraindicated in patients with a previous history of cholestatic jaundice/hepatic dysfunction associated with amoxicillin and clavulanate potassium. While amoxicillin/clavulanate possesses the characteristic low toxicity of the penicillin group of antibiotics, periodic assessment of organ system functions, including renal, hepatic, and hematopoietic function, is advisable if therapy is for longer than the drug is approved for administration. Prescribing amoxicillin and clavulanate potassium for oral suspension, in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

Amoxicillin and Clavulanate Potassium inhibits transpeptidase, preventing cross-linking of bacterial cell wall and leading to cell death. Addition of clavulanate increases drug's resistance to beta-lactamase. Amoxicillin is an antibiotic in a group of drugs called penicillin. Amoxicillin fights bacteria in the body. Amoxicillin and Clavulanate Potassium is a form of clavulanic acid, which is similar to penicillin. Clavulanate potassium fights bacteria that are often resistant to penicillin and other antibiotics. Amoxicillin and clavulanate potassium can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.