Amoxicillin and Clavulanate Potassium: Uses of Amoxicillin and Clavulanate Potassium

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Amoxicillin and clavulanate potassium is approved for treating the above infections only when they are caused by certain types of bacteria. Bacteria have difference resistance patterns in different regions in the country. This means that some bacteria may be susceptible to amoxicillin and clavulanate potassium in certain parts of the country but not in others. Overuse and inappropriate use of antibiotics can lead to antibiotic resistance. "Broad-spectrum" antibiotics should not be used to treat infections that could be treated by an antibiotic with a narrower spectrum of activity. Amoxicillin and clavulanate potassium is usually considered a broad-spectrum antibiotic. The drug should not be used unless tests have shown that a particular infection is caused by bacteria that are susceptible to it or if there is reason to strongly suspect that the bacteria are susceptible to the medication.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Amoxicillin and clavulanate potassium can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control to prevent pregnancy while taking amoxicillin and clavulanate potassium. Amoxicillin is a semi synthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative microorganisms. Amoxicillin is susceptible to degradation by ß-lactamases, and therefore, the spectrum of activity does not include organisms which produce these enzymes. Clavulanic acid is a ß-lactam, structurally related to the penicillin’s, which possesses the ability to inactivate a wide range of ß-lactamase enzymes commonly found in microorganisms resistant to penicillin’s and cephalosporin’s. It has good activity against the clinically important plasmid-mediated ß-lactamases frequently responsible for transferred drug resistance.